Gene polymorphisms in the nucleotide excision repair pathway and lung cancer susceptibility / 国际肿瘤学杂志
Journal of International Oncology
; (12): 126-130, 2013.
Article
em Zh
| WPRIM
| ID: wpr-431584
Biblioteca responsável:
WPRO
ABSTRACT
Nucleotide excision repair (NER) pathway is one of the principal ways of the repair of DNA damage.The single nucleotide polymorphisms (SNP) of its key genes such as xeroderma pigmentosum group A (XPA) gene,excision repair cross complementingl (ERCC1) gene and xeroderma pigmentosum group D (XPD) gene may be associated with differences in the DNA repair capacity and may influence an individual's risk of lung cancer,because the variant genotype in those polymorphisms might destroy or alter repair function.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2013
Tipo de documento:
Article