The effects of plasma 5-HT content with depressive patients treated by Turtle-Dragon decoction combined with acupuncture / 国际中医中药杂志

ABSTRACT

Objective To observe HAMD,SDS scores and plasma 5-tT content with Depressive Patients treated by Turtle-Dragon decoction combined with acupuncture.Methods 70 patients were randomly divided into the treatment group and the control group,the treatment group treated with the turtle dragon decoction combined with acupuncture,the control group treated with fluoxetine hydrochloride,all patients before treatment and after treated 8 weeks were measured by HAMD,SDS and detected by plasma 5-HT content.Results Two groups of patients after 8 weeks of treatment,the total effective rate was 80％ in the treatment group,the total effective rate was 85.71％ in the control group,two groups showed no significant difference (x2=0.40,P＞0.05).HAMD and SDS[the treatment group were(9.31 ± 2.10) points,(55.91± 4.13) points,the control group were(9.36±2.28)points,(56.70±3.77)points] scores were significantly lower(P＜0.01) than before treatment[the treatment group were(12.79±2.50)points,(61.54±3.26)points,the control group were(11.89±2.73)points,(62.09±3.24)points] in all the patients,Plasma 5-HT content[the treatment group were (118.62 ± 29.74) ng/ml,the control group were (121.10 ± 30.56) ng/ml] has been significantly improved (P＜0.01) after treatment[the treatment group were(65.97±23.35)ng/ml,the control group were(63.40±21.24) ng/ml] in all the patients.Between the two groups of patients after treatment,the comparison of the HAMD,SDS scores and Plasma 5-HT content was no significant difference (P ＞ 0.05).Conclusion Turtle-Dragon decoction combined with acupuncture can obviously improve the HAMD,SDS scores and plasma 5-HT content with Depressive Patients.Also treatments between two groups have equivalent effects.