Effect of Gegen Qinlian Decoction on Rotavirus-inducing Diarrhea in Neonatal Mice / 中国中医药信息杂志
Chinese Journal of Information on Traditional Chinese Medicine
; (12): 35-37, 2013.
Article
em Zh
| WPRIM
| ID: wpr-438872
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the anti-rotavirus effect of Gegen Qinlian decoction on rotavirus (RV)-inducing diarrhea neonatal mice model, and provide evidences for pharmacological and pharmacodynamic studies. Methods Neonatal diarrhea mice model of Kunming family infected with RV-Wa was developed. Symptom, diarrhea ratio and severity level, histological changes of neonatal mice’s small intestine and lung was assessed after Gegen Qinlian decoction (0.78 g/kg) treatment. Results Diarrhea ratio, diarrhea severity level, histological changes of neonatal mice’s small intestine and lung were obviously decreased after Gegen Qinlian decoction (0.78 g/kg) treatment. Conclusion Gegen Qinlian decoction has anti-rotavirus effect on RV induced diarrhea.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Information on Traditional Chinese Medicine
Ano de publicação:
2013
Tipo de documento:
Article