A strain of extensively drug resistant and KPC-2 carbapenemase-producing Kleb-siella pneumoniae is identified in Dongguan,Guangdong province / 中国感染与化疗杂志
Chinese Journal of Infection and Chemotherapy
; (6): 465-468, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-440443
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the extensively drug resistant mechanism and clinical treatment strategy of Klebsiella pneu-moniae .Methods The isolate was identified by Vitek2 Compact System.Antimicrobial susceptibility testing was conducted by Kirby-Bauer method.KPC-2 carbapenemase was detected by modified Hodge test.The gene encoding KPC-2 carbapenemase was amplified by polymerase chain reaction (PCR)and then sequenced.Results The strain was resistant to all antibiotics used in routine antimicrobial susceptibility testing except amikacin.Modified Hodge test showed positive result.KPC-2 gene was detected by PCR.The sequence was consistent with that of 11844849 in GenBank.After treatment for one month,no exten-sively drug resistant K.pneumoniae strain was detected from the patient.Conclusions It is necessary to strengthen the monito-ring and improve the awareness of extensively drug resistant K.pneumoniae for better control of such infections.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Infection and Chemotherapy
Ano de publicação:
2013
Tipo de documento:
Artigo