Effects of Deanxit on depression and clinical outcomes in elderly patients with acute coronary syndrome / 中华行为医学与脑科学杂志
Chinese Journal of Behavioral Medicine and Brain Science
; (12): 911-913, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-441924
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate deanxit clinical efficacy of depression in elderly patients with acute coronary syndrome(ACS).Methods 88 elderly patients with ACS and depression were randomly divided into Deanxit (2 tablets daily ; Deanxit,n =43) or placebo (control,n =45) treatment in addition to standard therapy.SDA score,SDS score,MACE and cardiac autonomic nerve function were performed at 12 weeks follow-up.Results In deanxit group,SDA score and SDS score were significantly reduced (34.28 ± 6.35 vs 52.68 ± 5.74,41.19 ±4.63 vs 54.68 ± 4.32,P < 0.05),MACE were also decreased (4.6% vs 28.9 %,P < 0.05).SDNN were significantly higher than control (109.03 ± 23.08 vs 98.29 ± 27.44,P < 0.05),but LF was reduced (152.89 ± 92.75vs 249.21 ± 64.17,P< 0.05).Conclusion Deanxit can improve the depression and clinical symptoms in elderly patients with ACS and depression.By improving the cardiac autonomic nerve function,deanxit possible reduce the onset of severe arrhythmia and improve the short-term prognosis.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio clínico controlado
/
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Journal of Behavioral Medicine and Brain Science
Ano de publicação:
2013
Tipo de documento:
Artigo