Study on differentially expressed serum proteins in Uyghur patients with primary hyperuricemia / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 792-794, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-442876
Biblioteca responsável:
WPRO
ABSTRACT
2-Dimensional gel electrophoresis and matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry (MALDI-TOF-MS) were used to screen differentially expressed serum proteins in Uyghur patients with hyperuricemia and control subjects.Western blot was used to validate differential proteins.Gel-image analysis revealed that there were 11 differential protein spots.A total of 4 differential protein spots were successfully identified by MALDI-TOF-MS.Complement 3,complement 4,haptoglobin,and apolipoprotein Al levels were up-regulated in patients as compared with controls.The result of complement 3 expression was validated by Western blot,which is accordant with that of proteomics.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Endocrinology and Metabolism
Ano de publicação:
2013
Tipo de documento:
Artigo