Research Progress of protective effect of intestinal trefoil factor on the gastrointestinal tract / 医学研究生学报
Journal of Medical Postgraduates
; (12): 439-443, 2014.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-446165
Biblioteca responsável:
WPRO
ABSTRACT
Intestinal trefoil factor (ITF or TFF3) is a member of trefoil factor family which is most studied , mainly in the in-testinal tract .TFF3 plays an important role in gastrointestinal mucosal protection and epithelial repair .Action mechanism includes in-teraction with mucin, migration, anti-apoptosis, angiogenesis, immune regulation, interaction with its receptor, etc.Recombinant TFF3 has been approved as a national drug and its therapeutic indications for repair mucosa , prevention and treatment of gastrointesti-nal ulcers and inflammation .Furthermore, the classic TFF3 receptor and signaling pathway is highly valuable to make TFF 3 become an effective treatment for gastrointestinal injury disease .
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Medical Postgraduates
Ano de publicação:
2014
Tipo de documento:
Artigo