Effectiveness of Danning Tablet in patients with non-alcoholic fatty liver of damp-heat syndrome type: a multicenter randomized controlled trial / 中西医结合学报
Journal of Integrative Medicine
; (12): 128-33, 2008.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-449424
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To evaluate the efficacy and safety of Danning Tablet (DNT) in patients with non-alcoholic fatty liver disease (NAFLD) of damp-heat syndrome type.METHODS:
A multicenter, randomized, double-blinded and positive drug parallel controlled trial was performed. One hundred and thirty-five patients were enrolled into the study and divided into two groups DNT-treated group (n=102) and ursodeoxycholic acid (UDCA)-treated group (n=33). Body mass index (BMI), principal symptoms, liver function, blood lipids, iconographic, and compositional parameters were measured before and after treatment, respectively.RESULTS:
In the two groups, BMI, distress in hepatic region, fatigue, anorexia, liver function, blood lipids and iconographic parameters were significantly improved, and the improvements of BMI, distress in hepatic region were better in DNT-treated group than in UDCA-treated group. The histological study also showed that DNT had positive effect in treatment of NAFLD.CONCLUSION:
DNT is an effective drug to treat patients with NAFLD of damp-heat syndrome type and is more effective than UDCA.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.5 Prevenção e tratamento do consumo de substâncias psicoativas
Problema de saúde:
Meta 3.5 Prevenção e tratamento do consumo de substâncias psicoativas
/
Álcool
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio clínico controlado
Idioma:
Inglês
Revista:
Journal of Integrative Medicine
Ano de publicação:
2008
Tipo de documento:
Artigo