Function of Toll like receptor signaling pathway in the carcinogenesis process related to high risk HPV infection of cervical / 国际肿瘤学杂志

ABSTRACT

Toll like receptors (TLRs) are the most characteristic of pathogen recognition receptors.TLR signal pathway affects the outcome of cervical HPV infection,and plays double roles of promoting or inhibiting tumor in immune regulation for the process from high-risk HPV infection to cervical cancer.The polymorphism of TLR gene is closely related to the occurrence of cervical cancer.