Two Cases of Infant-onset Cutaneous Mastocytosis / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
; : 105-108, 2012.
Article
em Ko
| WPRIM
| ID: wpr-47108
Biblioteca responsável:
WPRO
ABSTRACT
Mastocytosis is a rare disease in infants and children that characterized by a pathologic increase and accumulation of mast cells in one or more organs. Cutaneous mastocytosis is a typical presentation of pediatric-onset mastocytosis and often presents classical symptoms and signs related with mast cell mediator including pruritus, flushing, abdominal pain and Darier's sign. We present our experience with two rare cases of cutaneous mastocytosis, a 3-month-old boy and a 4-month-old boy. The former had a recurrent single brownish plaque with yellowish bullae in right forearm without any other symptom or sign. The latter had multiple brownish plaques in his trunk and extremities with intermittent diarrhea and Darier's sign. In each, a punch biopsy confirmed the diagnosis of solitary mastocytoma and urticaria pigmentosa. After 2weeks of anti-histamine and leukotriene antagonist therapy for symptom relief, both infants had no remnant skin lesion or symptoms.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Prurido
/
Pele
/
Biópsia
/
Mastocitose
/
Urticaria Pigmentosa
/
Dor Abdominal
/
Vesícula
/
Mastocitoma
/
Mastocitose Cutânea
/
Doenças Raras
Limite:
Child
/
Humans
/
Infant
Idioma:
Ko
Revista:
Clinical Pediatric Hematology-Oncology
Ano de publicação:
2012
Tipo de documento:
Article