Semen and serum anti-sperm antibodies in male infertility test correlation analysis / 国际检验医学杂志

ABSTRACT

Objective To discussion and analysis of the significance of semen and serum anti‐sperm antibodies in the test in male infertility.Methods 95casesofinfertilemalepatientsassubjectsinthisstudyfromJune2012toMay2014tocometoourhospi‐tal ,others choose to our hospital after medical investigation and no normal healthy male infertility 30 cases as controls group ,meas‐ured in blood and semen of anti‐sperm antibodies content and semen examination ,analysis and comparison .Results Semen of pa‐tients in the observation group sperm viability ,semen liquefaction time and a + b grade sperm motility percentages were lower than in the control group healthy men ,the two groups was statistically significant (P<0 .05) .Sperm viability ,semen liquefaction time and a + b grade sperm motility percentage of patients AsAb positive group were lower than AsAb tested negative for infertile pa‐tients ,the two groups was statistically significant(P<0 .05) .Patients in the observation group IL‐2 ,IL‐6 ,and the content of TNF‐αcompared with the healthy control group of men increased significantly between the two groups was statistically significant (P<0 .05) .AsAb positive serum IL‐2 group ,and IL‐6 levels and AsAb negative groups are similar ,but TNF‐αcontent than AsAb tested negative patients was significantly increased ,the two groups was statistically significant (P<0 .05) .Conclusion Anti‐sperm anti‐bodies in the blood and semen parameters have some relevance ,semen and blood detection of anti‐sperm antibodies can be used as a means of diagnosis of infertility patients ,it is worth widely recommended .