Clinical efficacy and safety of doxazosin combined with desmopressin in treatment of nocturia in patients with benign prostatic hyperplasia / 中华全科医师杂志
Chinese Journal of General Practitioners
; (6): 50-52, 2016.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-489396
Biblioteca responsável:
WPRO
ABSTRACT
Thirty six patients aged 50-70 years with benign prostatic hyperplasia (BPH) received doxazosin and desmopressin treatment for 4 weeks.After treatment the International Prostate Symptom Scores (IPSS) and Quality of Life (QoL) scores of patients were significantly improved (17.4 ± 2.5 vs.11.8 ± 1.1 and 3.9 ±0.6 vs.1.8 ± 1.3,respectively;both P < 0.01).The nocturia frequency was decreased from 4.6±1.5 to 2.1±1.6 (P<0.01);nocturnal urine output from (564±73) to (348±45) ml (P<0.05);the hours of undisturbed sleep increased from (88.6 ± 17.5) min to (146.2 ± 12.8) min (P <0.05).There were no significant differences in serum levels of sodium,potassium and chlorine,and osmoticpressure before and after treatment.The results indicate that doxazosin combined with desmopressin is safe and effective for treatment of nocturia in patients with BPH.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Aspecto:
Preferência do paciente
Idioma:
Chinês
Revista:
Chinese Journal of General Practitioners
Ano de publicação:
2016
Tipo de documento:
Artigo