The Detection and Clinical Value of Soluble Triggering Receptor Expressed on Myeloid Cells-1in Patients with Stable Chronic Obstructive Pulmonary Disease / 实用医学杂志
The Journal of Practical Medicine
; (24): 1609-1612, 2016.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-493592
Biblioteca responsável:
WPRO
ABSTRACT
Objective To determine the value of soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) in patients with stable chronic obstructive pulmonary disease (sCOPD). Methods From 2015 January to 2015 August, 101 patients with stable chronic obstructive pulmonary disease and 81 healthy controls were en-rolled. All subjects underwent pulmonary function test to record FEV1%pred and FEV1%FVC and their serum sTREM-1 levels were determined. Arterial blood gas analyses and COPD assessment tests were also conducted in stable COPD patients. Results Serum sTREM-1 levels were significantly higher in stable COPD patients than healthy controls (113.2 ± 31.5 pg/mL and 83.8 ± 17.9 pg/mL respectively, P=0.000). sTREM-1 levels were posi-tively correlated with CAT score (r=0.507, P=0.000), whereas negatively correlated with FEV1%pred and PaO2 (r = 0.507, P = 0.000; r = 0.439, P = 0.000). Conclusion sTREM-1 is a promising biomarker to evaluate sCOPD in the future.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
Aspecto:
Preferência do paciente
Idioma:
Chinês
Revista:
The Journal of Practical Medicine
Ano de publicação:
2016
Tipo de documento:
Artigo