Application of Fisher component analysis to study chemical fingerprint feature similarities of Fructus Trichosanthis and its processed products / 国际药学研究杂志

ABSTRACT

Objective To explore whether the basic principle of Fisher component analysis(FCA)can be used in the catego?ry analysis of Fructus Trichosanthis fruit and its processed products. Methods Their fingerprints were established by using HPLC-PDAD,and the standard fingerprints of them were obtained by digitizing with quercetin as the internal reference peak. Then,their chemical fingerprint information was extracted by FCA and classified by quality model,and the classification results were compared with those classified by principal component analysis and standard atlas analysis. Results Fructus Trichosanthis and its processed products can be accurately divided into two categories by FCA. Conclusion FCA can extract the implied chemical information in fin?gerprints,and analyze them accurately.