Role of PI3 K/Akt/mTOR signaling pathway in hepatocellular carcinoma / 临床肝胆病杂志
Journal of Clinical Hepatology
; (12): 954-957, 2014.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-498949
Biblioteca responsável:
WPRO
ABSTRACT
Phosphatidylinositol 3-kinase,Akt,and the mammalian target of rapamycin (PI3K/Akt/mTOR)signaling pathway is shown to play a key role in the tumorigenesis,proliferation,metastasis,apoptosis,and angiogenesis of hepatocellular carcinoma (HCC)by regulating gene expression.The components and functions of PI3K/Akt/mTOR signaling pathway are briefly described,and the research advances in the action mechanism of PI3K/Akt/mTOR signaling pathway in the progression of HCC and related inhibitors are reviewed.It is disclosed that blocking the PI3K/Akt/mTOR signaling pathway may become a new therapy for HCC.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Clinical Hepatology
Ano de publicação:
2014
Tipo de documento:
Artigo