RASSF1A and RASSF1A methylation′s relationship with breast cancer / 实用肿瘤学杂志
Practical Oncology Journal
; (6): 372-375, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-499336
Biblioteca responsável:
WPRO
ABSTRACT
Breast cancer is one of the most common malignant tumors in women.Early diagnosis plays a very important role in the treatment of breast cancer.Recently,with the development of epigenetics,it gives us a new orientation for early detection for cancers.The most understood mechanism of epigenetics is DNA methyla-tion.Ras associated domain family 1A gene(RASSFlA)promoter methylation occurres in tumor′s early stage,and have a statistically concern with tumor′s TNM stage,invasiveness and outcomes.Moreover,DNA methylation can be reversed,so RASSF1A can be a promising candidate for early breast cancer detection biomarker,and can be a potential orientation for breast cancer treatment.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de rastreamento
Idioma:
Chinês
Revista:
Practical Oncology Journal
Ano de publicação:
2015
Tipo de documento:
Artigo