Analysis of ADR Reports Caused by Psychotropic Drugs in Children and Adolescent of Our Center / 中国药房
China Pharmacy
; (12): 627-631, 2016.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-501435
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To investigate the characteristics of ADR induced by psychotropic drugs in children and adolescent of our center,and to provide reference for clinical drug use.METHODS:
ADR induced by psychotropic drugs in children and adoles-cent reported by our center from 2005 to 2015 were investigated and analyzed retrospectively.RESULTS:
A total of 177 ADR were collected,of which the most cases were induced by antipsychotic drugs as risperidonal,olanzapine and quetiepine. The most com-mon ADR were central and peripheral nervous system disorders(117 cases,37.86%),followed by endocrine disorder(35 cases, 11.32%),heart rate and rhythm disorders(32 cases,10.35%)and liver and biliary system disorders(17 cases,5.50%). By the relative titer of haloperidol,most of ADR were induced by haloperidol with dose of 4 mg,6 mg and 8 mg once a day(34,29 and 53 cases). Most of cases occurred within a week(94 cases,53.11%).CONCLUSIONS:
To develop and strengthen clinical applica-tion and ADR monitoring of psychotropic drugs in children and adolescents should be regarded as the key to ensure drug use safety.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2016
Tipo de documento:
Artigo