Clinical observation of Drospirenone and Ethinylestradiol Tablets for preventing postoperative complications of induced abortion / 中国生化药物杂志

ABSTRACT

Objective To observe the clinical effect of postoperative complications in patients with induced abortion by taking Drospirenone and Ethinylestradiol Tablets.Methods 400 patients with induced abortion from November 2015 to May 2016 were randomly divided into the observation group and the control group,200 cases in each group.The control group was treated with routine antibiotic therapy.The observation group treatment with Drospirenone and Ethinylestradiol Tablets based on the control group, 1 per one night, 21d for a course of treatment, continuous use of 6 courses.Compared the 2 groups of patients with postoperative complications of pelvic infection,intrauterine adhesions,pregnancy,recurrent abdominal pain and two groups of postoperative recovery time of menstruation,vaginal bleeding,endometrial thickness.Results In the observation group after pelvic infection,uterine cavity adhesion,pregnancy,periodic abdominal pain incidence were 1.5%,0.5%,0.0%,1.5%,were significantly lower than that of the control group7.0%,3.5%,4.0%,5.5%(P<0.05);the observation group after menstruation recovery time,vaginal bleeding,endometrial thickness respectively(27.2 ±1.7) d,(6.2 ±1.4)d,(7.2 ±2.3) mm,were lower than the control group(32.5 ±6.0) d,(7.8 ±2.7) d,(5.0 ±2.4) mm,two groups of the difference was statistically significant(P<0.05).Conclusion After artificial abortion,taking Drospirenone and Ethinylestradiol Tablets can effectively reduce the incidence of complications,improve the quality of life of patients,the method is simple,safe,effective and good compliance.