Recent advances of ELAM-1 in targeted cancer therapy / 实用肿瘤学杂志
Practical Oncology Journal
; (6): 444-447, 2016.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-504364
Biblioteca responsável:
WPRO
ABSTRACT
Endothelial leukocyte adhesion molecule -1 ( ELAM -1 ) is a member of the cell adhesion molecules,which plays a great role in the distant metastasis of tumor in ligand interactions between sLe (x)and sLe(a).Recently,it becomes a new research hotspot on applying ELAM -1 in targeted cancer therapy.Many studies results show that by regulation of ELAM -1 in biological effects ,such as ELAM-1 and ligand inhibitors , monoclonal antibody ,targeting gene ,and other mediates of the path of blocking therapy ,thereby inhibiting or bloc-king tumor distant metastasis ,so as to achieve the purpose of tumor therapy and improve the prognosis .Therefore , ELAM-1 is expected to exert a critical role in the tumor targeted therapy .In this paper ,the application value of ELAM-1 in tumor related targeted therapy is reviewed .
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Practical Oncology Journal
Ano de publicação:
2016
Tipo de documento:
Artigo