Pathogenesis and new therapeutic targets of liver fibrosis / 临床肝胆病杂志
Journal of Clinical Hepatology
; (12): 409-412, 2017.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-505910
Biblioteca responsável:
WPRO
ABSTRACT
In recent years,the basic research on liver fibrosis has been progressed rapidly.This article briefly reviews the cellular and molecular mechanisms of liver fibrosis,including the origin of myofibroblasts,immune regulation,autophagy,and epigenetic regulation,and introduces several new therapeutic targets.More and more evidences show that successful removal of causes is the most important antifibrotic therapy.At present,although the antifibrotic drugs acting on different targets have been emerging,most of them are still in the early stage of research and development,and well-designed clinical trials are needed to confirm their clinical efficacy.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de etiologia
Idioma:
Chinês
Revista:
Journal of Clinical Hepatology
Ano de publicação:
2017
Tipo de documento:
Artigo