Expression and role of Golgi phosphoprotein 3 in cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 27-30, 2017.
Article
em Zh
| WPRIM
| ID: wpr-509206
Biblioteca responsável:
WPRO
ABSTRACT
Golgi phosphoprotein 3 (GOLPH3 )is closely related to the development and prognosis of cancer,such as non-small cell lung cancer,breast cancer,gastric cancer,esophageal cancer,colorectal cancer,etc.The mainly tumor pathogenisis related GOLPH3 includes modulating the response to DNA damage, vesicle trafficking,mTOR signaling pathway,mitochondrial functions,cytokinesis and Golgi vesicular malignant secretion,and then promoting cell proliferation,invasion and metastasis.GOLPH3 is expected to be a new tar-get for cancer therapy,which may become an important biomarker for the diagnosis,treatment and prognosis of cancer.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2017
Tipo de documento:
Article