Research progress on the changes of subchondral bone in osteoarthritis and its molecular mechanisms / 复旦学报(医学版)
Fudan University Journal of Medical Sciences
; (6): 231-237, 2017.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-512733
Biblioteca responsável:
WPRO
ABSTRACT
Osteoarthritis (OA) is one of the most common chronic osteoarthritic diseases,which can involve the whole joint.Subchondral bone is an important part of the joint and has a close relationship to the development of OA.The changes and mechanisms of subchondral bone in OA are complex and remain disputes.In this review,we will discuss the advances of the molecular mechanisms of subchondral bone in OA,which include the pathological changes and the roles of the OPG/RANKL/RANK system,transforming growth factor β (TGFβ),estrogen-estrogen receptors and lipid metabolism in OA.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Fudan University Journal of Medical Sciences
Ano de publicação:
2017
Tipo de documento:
Artigo