Oxygen Uptake Efficiency Slope Predicting the Prognosis in Patients With Idiopathic Pulmonary Arterial Hypertension / 中国循环杂志
Chinese Circulation Journal
; (12): 367-371, 2017.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-513857
Biblioteca responsável:
WPRO
ABSTRACT
Objectives:
To explore weather oxygen uptake efficiency slope (OUES) may predict the prognosis in patients with idiopathic pulmonary arterial hypertension (IPAH).Methods:
The consecutive newly diagnosed IPAH patients in our hospital from 2010-11 to 2015-06 were prospectively enrolled and regular follow-up study was conducted to record cardiovascular events (death and lung transplantation). Kaplan–Meier curve, uni- and multivariate Cox regression analysis were performed to assess the survival rate in relevant patients.Results:
A total of 210 IPAH patients at the mean age of (32±10) years were finished cardiopulmonary exercise test (CPET) and received regular follow-up study including 159 female. There were 31 patients died and 1 received lung transplantation over 41 months follow-up period. OUES was positively related to peak oxygen uptake (VO2)/body weight (r=0.71, P0.52 L/(min?m2) (41.9% vs 89.8%), P<0.0001.Conclusion:
OUES as a submaximal CPET parameter may well predict the prognosis in IPAH patients.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Circulation Journal
Ano de publicação:
2017
Tipo de documento:
Artigo