Inhibitory Effects of Ethanol Extracts Obtained from Five Traditional Chinese Medicines on Experimental Hypermelanosis Induced by UVB Using a Brownish Guinea Pig Model / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)1994.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-517399
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the inhibitory effects of traditional Chinese medicine (TCM) on hypermelanosis and provide experimental evidence for treating skin pigmentary disorders. Methods Five TCMs with strong inhibitory effects on tyrosinase activity were tested. The changes of the number and morphology of melanocytes induced by UVB were observed in the experimental hypermelanosis model (brownish guinea pig). Results Decreased melanocytes and melanin granules were found with the treatment of Poria cocos, Polyporus umbellatus, Cornus officinalis Sieb. et Zucc., Atractylodes macrocephala Koidz., Astoagalus complanatus R. Br. ex Bge. Conclusion There are inhibitory effects on hypermelanosis induced by UVB with the treatment of Poria cocs, Polyporus umbellatus, Cornus officinalis Sieb.et Zucc., Atractylodes macrocephala Koidz., Astoagalus complanatus R. Br.ex Bge.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Dermatology
Ano de publicação:
1994
Tipo de documento:
Artigo