Preliminary results of combined high intensity focused ultrasound and radiotherapy on rectal carcinoma in 121 cases / 中国普通外科杂志

ABSTRACT

Objective To assess therapeutic effects and safety of high intensity focused ultrasound ( HIFU ) and radiotherapy for the treatment of rectal carcinoma. Methods In combination with low dose of radiotherapy, we treated 121 cases of rectal carcinoma with FEP BY01 type HIFU therapy from Jul.1998 to Dec.2000 and 43 cases were followed up for more than one year. ResultsComplete response (CR) was achieved in 27 cases(22%), partial response (PR) in 80 cases (66%),and no change(NC)was found in 14 cases (12%) with a total response rate of 88 4%.There were no complications. One year survival rate was 81%(35/43) and 2 year survival rate was 77%(23/30). ConclusionHIFU in combination with radiotherapy is a new method to treat rectal carcinoma with significant therapeutic effect and high safety.