Expression of carbohydrate antigen72-4 in surgically removed lymph nodes and its diagnostic value on micrometastases in patients with gastric carcinoma / 中国普通外科杂志

ABSTRACT

ObjectiveTo study the relationship between the expression of carbohydrate antigen 72-4(CA72-4) in pathology negative lymph nodes from patients with gastric carcinoma and micrometastases. MethodsA total of 385 perigastric negative lymph nodes from 65 patients were immunohistochemically stained with tumor-associated glycoprotein by S-P. ResultsThe lymphatic micrometastases of gastric carcinoma were identified in 14 of 65 patients (21.5%) and in 26 of 385 negative-nodes (6.8%). The incidence of micrometastases was significantly higher in patients with diffuse type than intestinal type(35.5% vs. 8.8%,P