Effects on Gastric Secretion and Anti-gastric Ulcer Action of Sea Buckthorn Pulp Oil in Rats / 中国药房
China Pharmacy
; (12)2001.
Article
em Zh
| WPRIM
| ID: wpr-521137
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:To study the effects on gastric secretion and anti-gastr ic ulcer action of sea buckthorn pulp oil(SBPO)in rats METHODS:The effects of SB PO on gastric secretion in rats were studied with pylorus ligation The anti-ga stric ulcer actions of SBPO was observed on the gastric ulcer models induced by water immersion stress,reserpine,pylorus ligation or acetic acid The analgesi c effect was tested by the hot-plate method and writhing method RESULTS:SBPO significantly inhibited the secretion of gastric acid and pepsin and promoted th e secretion of gastric mucus SBPO markedly protected the formation of gastric u lcer induced by water immersion stress,reserpine or pylorus ligation and promot ed the healing of acetic acid induced gastric ulcer SBPO significantly decrease d the number of twisting body in mice CONCLUSION:SBPO has anti-gastric ulcer effect The mechanisms of anti-gastric ulcer action might be its effects of inh ibition of the secretion of gastric juice,promotion of the secretion of gastric mucus and analgesic effect
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
China Pharmacy
Ano de publicação:
2001
Tipo de documento:
Article