Studies on hepatic carcinoma cell invasion in vitro through Rho/Rho kinase pathway / 中国普通外科杂志
Chinese Journal of General Surgery
; (12)1997.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-524588
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the role of Rho/Rho kinase -associated cell migration of hepatic carcinoma cell line and inhibition of tumor cell invasion by Rho kinase inhibitor Y-27632. Methods Western blot was used to estimate the expression of Rho protein in the cells. After treatment of SMMC7721 cell with Y-27632, cell biological behaviors such as colony-forming efficiency, adhesiveness, cell motility, in vitro invasiveness, metastatic potential were observed. Results The ability of Y-27632 treated SMMC7721 cells to invade the reconstituted basement membrane decreased significantly ( P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of General Surgery
Ano de publicação:
1997
Tipo de documento:
Artigo