The expressions and clincal significance of PTEN and pAkt in hepatocellular carcinoma / 中国医师杂志
Journal of Chinese Physician
; (12)2000.
Article
em Zh
| WPRIM
| ID: wpr-526335
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the expressions and clinical significance of the tumor supressor gene phosphatase and tensin homlog deleted on chromosome ten protein(PTEN) and oncogene phosphoserine/threonine protein kinase B(phospho-serine/threonine protein kinase Akt/PKB,pAkt) in hepatocellular carcinoma(HCC).Method The expressions of PTEN and pAkt in 65 cases of HCC and their pericarcinomatous tissues were detected by immunohistochemical staining with S-P method.Results The positive expression rate of PTEN in HCC was significantly lower than that in pericarcinomatous liver tissues,and the positive rate of pAkt was significantly higher than that in pericarcinomatous liver tissues(all P
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Chinese Physician
Ano de publicação:
2000
Tipo de documento:
Article