Effect of signal transducer and activator of transcription 6 and its mRNA on airway inflammation in a rat asthma model / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12)1986.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-526543
Biblioteca responsável:
WPRO
ABSTRACT
AIM:
To study the effect of signal transducer and activator of transcription 6 (STAT6) on airway inflammation of rats with asthma.METHODS:
Male Sprague-Dawley rats were randomly divided into control group and asthma group. The lung tissue was sampled from the left lung. Bronchoalveolar lavage fluid (BALF) was collected from the right lung. The concentrations of IL-4 in serum and BALF were measured by sandwich ELISA. STAT6 protein and STAT6 mRNA were observed in the epithelial cells of bronchus by the technique of immunohistochemistry and in situ hybridization.RESULTS:
(1) The concentrations of IL-4 in BALF and serum of asthma group were significantly higher than those in control group (P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Pathophysiology
Ano de publicação:
1986
Tipo de documento:
Artigo