Effects of SDZ on LOVO Cell Line and the Expression of E-Cadherin and N-Cadherin / 中国药房
China Pharmacy
; (12)2007.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-531610
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To investigate the effects of SDZ on LOVO cell line and the expression of E-Cadherin and N-Cadherin.METHODS:
The apoptosis of SDZ on growth of LOVO cells was observed under electron microscope and inverted microscope. The expression of E-Cadherin and N-Cadherin treated by SDZ were detected by RT-PCR.RESULTS:
SDZ promoted the apoptosis of LOVO cell lines and increased the expression of E-Cadherin,however,it did no effect on the expression of N-Cadherin.CONCLUSION:
SDZ can enhance the intercellular adhesiveness and degrade the capability of infiltration and metastasis of tumor cells.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2007
Tipo de documento:
Artigo