Determination of Cytarabine and Uracil Arabinoside in Tissues of Rats by RP-HPLC / 中国药房
China Pharmacy
; (12)2007.
Article
em Zh
| WPRIM
| ID: wpr-534417
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WPRO
ABSTRACT
0.998 8).The minimum detection limit were 0.1~0.4 mg?L-1.The average recovery rates were no less than 96%(RSD≤7.19%).There were significant difference among the concentration of Ara-C and Ara-U in plasma,cerebrospinal fluid and testicular tissue.Ara-C in plasma hadn't been determined in low-dose group and medium-dose group except for Ara-U.CONCLUSIONS: The method is simple,rapid,accurate and reproducible for plasma concentration monitoring and pharmacokinetic study of Ara-C and Ara-U.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
China Pharmacy
Ano de publicação:
2007
Tipo de documento:
Article