AGING CHANGES IN TYROSINE HYDROXYLASE IMMUNOREATIVE NEURONS IN THE LOCUS COERULEUS OF THE RAT / 西安交通大学学报(医学版)

ABSTRACT

Aging changes of tyrosine hydroxylase (TH) -immuno reactive neurons in the locus coeruleus were examined in young (3 month-old). adult(12 month-old) and aged(20 month-old) Wistar male rats, using the IGSS method and image quantitative analysis. The results obtained are as follows ① The number of TH-immunoreactive neurons docreased markedly (P