THE EFFECT OF DL-TETRAHYDROPALMATINE AND SINOMEMINE ON THE MOTILITY OF OVIDUCT SMOOTH MUSCLE IN RABBITS / 西安交通大学学报(医学版)

ABSTRACT

The effects of DL-tetrahydropalmatine andsinomemine on the activity of oviduct smooth mus-cle and ovum transport in rabbits are reported inthis paper. The results indicate that the two a-gents apparently inhibit the contractile activity ofoviduct isthmic smooth muscle of rabbit in vitroand decrease the frequency, amplitude, tensionand curve areas of the contraction. The contractileffect induced by noradrenaline is also inhibited re-markbly by them. In addition, DL-THP and Sino.can delay ovum transport in rabbit oviduct after ivHCG 48 h. It is suggested that the inhibition ofactivity of oviduct smooth muscle may be one ofthe important causes of delaying egg transportcaused by the two agents.