STUDY ON THE CLINICAL APPLICATION OF TELOMERASE ACTIVITY BY FINE NEEDLE ASPIRATION FOR PREOPERATIVE DIAGNOSIS OF BREAST CANCER / 中国现代普通外科进展
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-535550
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To investigate the value of the clinical application of telom-erase activity by fine needle aspiration from breast masses for preoperative diagnosis of breast cancer in order to provide scientific basis for its practical clinical application.Methods:
85 patients with breast masses were aspirated by fine needles in the study. The samples obtained by aspiration were detected with telomerase activity by telomeric repeat amplification protocol (TRAP) assay and observed with cytomorphology by microscope respectively. The sensitivity, specificity and Youden's index of the two detective methods in diagnosis for breast cancer were compared respectively while postoperative paraffin slice pathologic results were considered as the final standard.Results:
Compared with cytomorphology by microscope,preoperative telomerase activity detection's specificity which is 73.9% versus 82.6%(P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
/
Guia de prática clínica
Idioma:
Chinês
Revista:
Chinese Journal of Current Advances in General Surgery
Ano de publicação:
1999
Tipo de documento:
Artigo