Intravesical epirubicin instillation for preventing the recurrence of superficial bladder tumors after surgical management / 中华泌尿外科杂志

ABSTRACT

Objective To evaluate intravesical epirubicin instillation for preventing the recurrence of superficial bladder tumors after surgical management. Methods From Aug.1998 to Aug.1999, 32 cases of superficial bladder tumors after TURBt or partial cystectomy, received early single intravesical epirubicin instillation and the patients have been followed up for 12～24 months with cystoscopy. Results The patients followed up from 12～24 months after surgery(average time was 18 months).In 4 patients the tumor recurred 3, 6, 7 and 8 months after surgery.No side effect and complication was observed either during or after the instillation. Conclusions Early single intravesical epirubicin instillation is markedly effective for preventing the recurrence of superficial bladder tumors after surgical management. Its toxic side effects are mild. This method is of high clinical value.