The effects of transfection of a truncated BMP-II receptor on the prolife ration of Tca8113 cells / 实用口腔医学杂志
Journal of Practical Stomatology
; (6)2000.
Article
em Zh
| WPRIM
| ID: wpr-538774
Biblioteca responsável:
WPRO
ABSTRACT
Objective: To study the effects of BMPs signals on the proliferation of tongue cancer Tca8113 cells. Methods: Th e cDNA of truncated BMP-II receptor was transfected into Tca8113 cells by usin g FuGENE6 transfection kit, the transfected cells were named Tca8113ZR. The pro liferation and DNA synthesis of Tca8113 and Tca8113ZR cells were investigated b y MTT assay,FCM and BrdU analysis. Results: In MTT assay the A value of Tca8113 and Tca8113ZR cells was 0.47?0.01 and 0.35?0.01 (P0.05).Conclus ion: BMPs might be involved in the development of squamous cell carc inoma of tongue.
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1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Practical Stomatology
Ano de publicação:
2000
Tipo de documento:
Article