Advances in Overcoming Multidrug Resistance of Tumors Caused by mdr1 Gene / 中国普外基础与临床杂志
Article
em Zh
| WPRIM
| ID: wpr-540425
Biblioteca responsável:
WPRO
ABSTRACT
Objective To review the advances in overcoming multidrug resistance of tumors caused by mdr1 gene. Methods Different ways of overcoming multidrug resistance of tumors caused by mdr1 gene in the literatures were reviewed. Results One of the important reasons causing multidrug resistance was due to the overexpression of mdr1 gene and its product P-glycoprotein. There were two ways to overcome multidrug resistance of tumors through mdr1 genes mRNA and its product P-glycoprotein effectively.Conclusion The clinical test of the unitary way to overcome multidrug resistance of tumors is unsatisfactory, combining different ways to overcome multidrug resistance of tumors will be the hot spot of tumors research in the future.
Texto completo:
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Bases and Clinics in General Surgery
Ano de publicação:
2003
Tipo de documento:
Article