Detection and Analysis of Biomarker of Pregnant Woman Subjected to Passive Smoking / 环境与健康杂志

ABSTRACT

Objective To investigate the influence of passive smoking to pregnant woman's and fetus's health by the detection of biomarker. Methods A questionnaires about passive smoking made by ourselves were answered by 236 pregnant women including quantity and the number of year of smoking in the family and working places. At the same time pregnant woman's saliva, venous blood, urine and umbilical cord blood were collected. The sulphocyanate in their saliva was determined with pyridine-barbiturate method; the cotinine in venous blood, urine and umbilical cord blood were determined with barbiturate method. Results The content of sulphocyanate in saliva was different upon the quantity of passive smoking of pregnant women; there were significant differences had been seen among groups of passive smoking in cotinine in venous blood, urine and umbilical cord blood. Conclusion The contents of cotinine in venous blood, urine and umbilical cord blood are biomarkers of pregnant woman subjected to passive smoking, and passive smoking of pregnant woman will influence the health of pregnant woman and fetus.