Bone defect repair using allogenic ECM combined with chondrocytes in rabbits / 中国矫形外科杂志
Orthopedic Journal of China
; (24)2006.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-545706
Biblioteca responsável:
WPRO
ABSTRACT
[Objective]The characteristics and mechanism of the bone defect repair with the using allogenic extracellular cartilage matrix(ECM)were studied.[Method]Forty New Zealand white rubbits were divided into three groups at randomA and B on the right side,the defect was covered with the complex of ECM and autologous mesenchymal stem cells(MSCs),the ECM in the groups A and B,respectively.The defects on the left side served as controls correspondingly.The rabbits were killed at the 2nd,4th,6th,10th week.Samples were taken for radiological and histological studies.[Result]In the experimental sides the bone defects were healed.New bone appeared in the way of intramembranous ossification and entochondrostosis.[Conclusion]It is suggested that the complex of ECM and autologous MSCs has the effects on guiding bone regeneration and preventing from nonunion.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Orthopedic Journal of China
Ano de publicação:
2006
Tipo de documento:
Artigo