Advances in Research on Adverse Effect of Formaldehyde on Male Reproductive System / 环境与健康杂志

ABSTRACT

Formaldehyde is a chemical which is traditionally used as disinfectant and preservative. Recently,formaldehyde becomes raw material of adhesive which is widely used for indoor decoration. It has been recently reported in many animal experiments that formaldehyde had adverse effects on male reproductive endocrine,sperm quantity and quality,and but few reports were obtained about the adverse effects of formaldehyde on male reproductive system in human beings. Damage to genetic material,induced by lipid peroxidation and cell apoptosis is the possible mechanism of toxic effect. Male reproductive toxicity and mechanism of formaldehyde were discussed,and the recent researches were reviewed in the present paper.