Eosinophilic Ulcer of the Tongue / 대한피부과학회지

ABSTRACT

Eosinophilic ulcer of the tongue, which is characterized by an ulcer with indurated and elevated border that is usually covered by a pseudomembrane, is a benign reactive lesion. It rapidly develops, and spontaneously resolves in a few weeks. It occurs mostly on the tongue, and has a peak onset in the fifth to sixth decades of life. We experienced an eosinophilic ulcer of the tongue in a 65 years old man. The patient showed a single ulcer on right side of his tongue, but had neither subjective symptom nor previous oral or genital ulcers, arthralgia, and erythema nodosum-like skin lesions. The ulcer was 1.2 cm sized with indurated border. Histopathologically, the lesion exhibited ulceration, and a mixed, dense cellular infiltrate composed of eosinophils, lymphocytes, and neutrophils extended from the dermis into muscular layer. The lesion had completely disappeared in two weeks, and did not recur yet for follow-up period of nine months. Only one case of eosinophilic ulcer of oral mucosa have been reported in the Korean dermatological literature, so it is the second case of eosinophilic ulcer of the tongue in Korea.