Preparation of Cartilage Antitumor Component and Its Effects on Human Tumor Cell Lines / 第二军医大学学报
Article
em Zh
| WPRIM
| ID: wpr-550988
Biblioteca responsável:
WPRO
ABSTRACT
Cartilage antuumor component (CATC) was isolated from a 1 mol/L guanidine hydrochloride extract of bovine cartilage by acetone fractioned precipitation and superfiltration. Using human skin fibroblasts as a normal control, it was demonstrated that CATC inhibited the DNA synthesis of Hela, QGY7703 tumor cell lines and bovine artery endothelial cells, but accelerated the normal cells, when the concentration was below 1250 ?g/ml. At the concentration of 5 000 ?g/ml, CATC inhibited the two cell lines. With human tumor stem cell assay, CATC inhibited the stem cell growth of Hela and QGY7703 cell lines. These suggest that CATC has the effects of inhibiting angiogenesis and tumor cells.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
1985
Tipo de documento:
Article