ELECTROPHYSIOLOGICAL MECHANISM OF ATRIAL FIBRILLATION INDUCED BY ACETYLCHOLINE IN DOGS / 解放军医学杂志

ABSTRACT

To study the electrophysiological mechanism of atrial fibrillation induced by acetylcholine(Ach). The results showed that①Ach decreased ERP of four atrial sites.When the concentration of Ach was incseased, ERP of 4 sites became shorter but COVERP became bigger.②As the concentration of Ach was increased, the percent of AF induced by Ach and AF was increased with the duration prolonged( P 0 05).③There was a significant correlation between atrial vulnerability with ERP and COVERP( P