THE METABONOMIC STUDY ON PORTAL BLOOD PLASMA OF RATS AFTER ORAL ADMINISTRATION OF QUERCETIN / 营养学报
Acta Nutrimenta Sinica
; (6)2004.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-562634
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To investigate the effects of quercetin on metabolic profiles of portal blood plasma in rats.Method:
Twenty five male Wistar rats were administered orally with 40 mg/kg bw quercetin. Portal blood was collected at 0,0.5h,1 h,2 h and 4 h after dosing respectively and analyzed by 1H NMR. The acquired data were subjected to partial least-squares discriminant analysis.Results:
The identified biochemical effects associated with quercetin dosing included increased plasma concentrations of dimethyl sulfoxide,lactate,glucose,alanine,glutamate,succinate,?-hydroxybutyrate,acetone and decreased plasma concentrations of citrate and tyrosine.Conclusion:
Quercetin may change the intestinal endogenous metabolism significantly in rats.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Acta Nutrimenta Sinica
Ano de publicação:
2004
Tipo de documento:
Artigo