The clinical application of early enteral nutrition in severe brain injury patients with mechanical ventilation / 肠外与肠内营养

ABSTRACT

Objective: To investigate the clinical effects of early enteral nutrition in severe brain injury patients requiring mechanical ventilation. Methods: 56 patients requiring mechanical ventilation were randomly divided into two groupsA(n=28),EEN group peptisorb,1 000 ml a day;B(n=28),control group,PN.The changes of serum total protein,blood albumin,immune globulin,lymphocyte count,nitrogen balance,oxgenation index(PaO2/FiO2),ventilation parameter and blood routine were measured.APACHE Ⅱ,incidence of ventilator-associated pneumoniasurvival rate for 28 days and days in hospital were observed.Results: Incidence of ventilator-associated pneumonia,28 d-survival rate and mean hospitalization day were significantly different(P