IMMUNOHISTOCHEMICAL LOCALIZATION AND QUANTIFICATION OF RGNTF AND ITS RECEPTOR IN RETINAE OF EMBRYONIC RATS / 解剖学报

ABSTRACT

Monoclonal antibody specific to the retinal ganglion neuronotrophic factor (RGNTF) and anti-idiotypic monoclonal antibody specific to the receptor of RGNTF were used to localize immunohistochemically and quantify the amounts of RGNTF and its receptor in the paraffin sections of embryonic E_(16) to E_(20) rat retinae. The results revealed that RGNTF contents in the retinal ganglion cells of E_(16) to E_(20) embryonic retinae decreased lineally and very significantly (P