The effects of arsenic trioxide on the expressions of cancerme tastasis associated genes / 中华消化杂志
Chinese Journal of Digestion
; (12)2001.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-570238
Biblioteca responsável:
WPRO
ABSTRACT
Objective To test the expression of five cancer metastasis associated genes indu ced by arsenic trioxide. Methods The expression of CD44,p53,nm23 ,H-r as and PCNA induced by arsenic trioxide were examined by immunohistochemistry me thod . Results Arsenic trioxide induced decrease of the expression of C D44,p 53 and PCNA in gastric cancer cells,and the expression of nm23 and H-ras were not changed by As_2O_3. Conclusions Arsenic trioxide inhibits the metastasis of gastric ca ncer cells through reducing the expression of cancer metastasis associated gene s.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Digestion
Ano de publicação:
2001
Tipo de documento:
Artigo