Determination of chlorogenic acid and baicalin in Ganmaozhike Granules by HPLC / 中成药

ABSTRACT

AIM: To establish the determination method of chlorogenic acid and baicalin in Ganmaozhike Granules (Flos Lonicerae,Radix Scutellariae,etc.). METHODS: The contents of chlorogenic acid and baicalin in Ganmaozhike Granules were determined by HPLC. RESULTS: The linear velation was good. The average recovery of chlorogenic acid was 101.9%,RSD was 1.12%;The average recovery of baicalin was 99.2%,RSD was 1.31%. CONCLUSION: The method is simple,accurate and with a good reproducibility and can be used for the quality control of the granules.