The relationship between MMP-9 serum level and disease activity in patients with systemic lupus erythematosus / 中华风湿病学杂志
Chinese Journal of Rheumatology
; (12)2001.
Article
em Zh
| WPRIM
| ID: wpr-572132
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the relationship between serum level of MMP-9(matrix metalloproteinase-9) and the disease activity of systemic lupus erythematosus(SLE).Methods Serum level of MMP-9 of 30 controls and 36 SLE patients were measured by Enzyme Linked Immuno Sorbent Assay.Results Significantly decreased serum level of MMP-9 was found in SLE patients as compared to that in healthy controls(108?113) ng/ml vs (352?155) ng/ml (P0.05).Conclusion The present data suggests that MMP-9 may be involved in the pathogenesis of SLE,and serum MMP-9 level may be a marker of disease activity,renal damage,disease progression and amelioration in SLE.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Rheumatology
Ano de publicação:
2001
Tipo de documento:
Article